Synthesis and antimicrobial activity of some new 4-hydroxy-2H- 1,4-benzoxazin-3(4H)-ones.

Ozden, S; Oztürk, A M; Göker, H; Altanlar, N

Ozden, S; Oztürk, A M; Göker, H; Altanlar, N.

Ozden S; Department of Pharmaceutical Chemistry, Faculty of Pharmacy, Ankara University, Tandogan, Turkey.

Farmaco ; 55(11-12): 715-8, 2000.

Article en En | MEDLINE | ID: mdl-11204947

ABSTRACT

ABSTRACT

Some 4-hydroxy-2H-1,4-benzoxazin-3(4H)-ones were synthesized and evaluated for their antimicrobial activities against Staphylococcus aureus, Escherichia coli and Candida albicans. Compounds 9, and 10 exhibited the best activity against Candida albicans.

Asunto(s)

Antiinfecciosos/síntesis química; Oxazinas/química; Antibacterianos; Antiinfecciosos/farmacología; Antifúngicos/síntesis química; Antifúngicos/farmacología; Candida albicans/efectos de los fármacos; Fenómenos Químicos; Química Física; Escherichia coli/efectos de los fármacos; Pruebas de Sensibilidad Microbiana; Oxazinas/farmacología; Staphylococcus aureus/efectos de los fármacos

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