Carcinogenic effects of Di-n-propylnitrosamine, beta-hydroxypropyl-n-propylnitrosamine, and methyl-n-propylnitrosamine on Sprague-Dawlay rats.
J Natl Cancer Inst
; 54(4): 937-43, 1975 Apr.
Article
en En
| MEDLINE
| ID: mdl-1127723
ABSTRACT
The carcinogenic effects of di-n-propylnitrosamine and its two related compounds, beta-hydroxypropyl-n-propylnitrosamine (HPPN) and methyl-n-propylnitrosamine (MPN), were tested in rats and compared. All three substances induced neoplasms in the nasal and paranasal cavities, esophagus, and liver. MPN treatment caused the highest tumor incidence in the esophagus, whereas HPPN induced the most hepatic tumors.
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Banco de datos:
MEDLINE
Asunto principal:
Carcinógenos
/
Neoplasias Experimentales
/
Nitrosaminas
Límite:
Animals
Idioma:
En
Año:
1975
Tipo del documento:
Article