Analogues of polyamine alkaloids and their synthetic advantages.

Li, Y; Popaj, K; Lochner, M; Geneste, H; Budriesi, R; Chiarini, A; Melchiorre, C; Hesse, M

Li, Y; Popaj, K; Lochner, M; Geneste, H; Budriesi, R; Chiarini, A; Melchiorre, C; Hesse, M.

Li Y; Organisch-chemisches Institut, Universität Zürich, Switzerland.

Farmaco ; 56(1-2): 127-31, 2001.

Article en En | MEDLINE | ID: mdl-11347953

ABSTRACT

ABSTRACT

Several polyamine derivatives were synthesized in order to produce novel antagonists of muscular nicotinic acetylcholine receptors. Their affinities were compared with those of philanthotoxin PhTX-343.

Asunto(s)

Antagonistas Nicotínicos/síntesis química; Poliaminas/síntesis química; Animales; Humanos; Antagonistas Nicotínicos/farmacología; Poliaminas/farmacología; Relación Estructura-Actividad

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Banco de datos: MEDLINE Asunto principal: Poliaminas / Antagonistas Nicotínicos Límite: Animals / Humans Idioma: En Año: 2001 Tipo del documento: Article

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Imprimir

XML

PubMed Links

Banco de datos: MEDLINE Asunto principal: Poliaminas / Antagonistas Nicotínicos Límite: Animals / Humans Idioma: En Año: 2001 Tipo del documento: Article