Syndecan-4 and focal adhesion function.
Curr Opin Cell Biol
; 13(5): 578-83, 2001 Oct.
Article
en En
| MEDLINE
| ID: mdl-11544026
ABSTRACT
Two groups have now reported the viability of mice that lack syndecan-4. These mice have wound healing/angiogenesis problems, and fibroblasts from these animals differ in adhesion and migration from normal. This is consistent with recent in vitro data indicating a need for signaling via syndecan-4 for focal adhesion formation, and reports that overexpression of proteins that bind syndecan-4 can modify cell adhesion and migration.
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Banco de datos:
MEDLINE
Asunto principal:
Proteoglicanos
/
Glicoproteínas de Membrana
/
Adhesiones Focales
Límite:
Animals
Idioma:
En
Año:
2001
Tipo del documento:
Article