[Neutralization of Venezuelan equine encephalomyelitis virus by anticellular serums]. / Neitralizatsiia virusa venesuél'skogo éntsefalomielita loshadei antikletochnymi syvorotkami

ABSTRACT

The results of the study of host antigens in Venezuelan equine encephalomyelitis virus by means of neutralization test in tissue culture using sera containing antibody for the species-specific antigens, Forssman antigen and group A and B antigens are presented. They show the inhibiting effect of the sera to be not uniform. The greatest neutralizing effect on the virus was exerted by immune sera to chick embryo fibroblasts and their fractions (by 0.5-3.9 lg PFU/ML). The lack of the virus neutralizing effect in sera for the Forssman antigen and for group A antigen appears to depend upon their deeper localization in the structure of virion.