[Synthesis of cholesterol-containing cationic amphiphiles with heterocyclic bases]. / Sintez kholesterinsoderzhashchikh kationnykh amfifilov s geterotsiklicheskimi osnovaniiami.

A number of cationic derivatives of cholesterol containing polar residues of N-methylimidazole, pyridine, N-methylmorpholine, and 4-N,N-dimethyaminopyridine were synthesized by the interaction of the corresponding heterocyclic bases with cholesterol 5-bromopentanoate followed by the treatment with methyl iodide in the case of tertiary amines. In addition, N-(4-cholesteryloxycarbonylbutyl)piperazine was obtained for the preparation of pH-sensitive liposomes.