Global high-throughput screens for cellular function.
Exp Hematol
; 30(5): 381-7, 2002 May.
Article
en En
| MEDLINE
| ID: mdl-12031643
ABSTRACT
There is a critical need for global methods that allow for high-throughput assessment of cellular function for clinical and basic scientists working in both academia and the pharmaceutical industry. These methods typically couple systematic inactivation strategies with high-throughput cell-based assays that facilitate rapid target validation. We present here a survey of these technologies and their applications. We discuss their promise and limitations in addressing the vast number of candidate molecules of disease relevance that are emerging from genomics and proteomics.
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Banco de datos:
MEDLINE
Asunto principal:
Fenómenos Fisiológicos Celulares
/
Tamizaje Masivo
Tipo de estudio:
Screening_studies
Límite:
Animals
/
Humans
Idioma:
En
Año:
2002
Tipo del documento:
Article