Pruritic dermatoses: overview of etiology and therapy.
Am J Med
; 113 Suppl 9A: 25S-33S, 2002 Dec 16.
Article
en En
| MEDLINE
| ID: mdl-12517579
ABSTRACT
This review begins with a brief survey of the neurophysiology and neuroanatomy of pruritus, and goes on to describe the etiology of the major allergic and nonallergic pruritic disorders. The etiology of pruritus often suggests the appropriate treatment. For example, urticaria, which is primarily mediated by histamine, is amenable to treatment with H1 antihistamines. Second-generation, nonsedating antihistamines appear to be more effective than sedating antihistamines, perhaps because of better compliance. Other systemic pharmacologic options may be useful in nonhistamine-mediated disorders, for example, immunomodulators for inflammation-induced pruritus or opiate antagonists for atopic dermatitis. Nonpharmacologic measures, such as proper skin care, and physical modalities, such as phototherapy or acupuncture, may also be helpful.
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Banco de datos:
MEDLINE
Asunto principal:
Prurito
/
Enfermedades de la Piel
Tipo de estudio:
Etiology_studies
Límite:
Humans
Idioma:
En
Año:
2002
Tipo del documento:
Article