[Preparation of monospecific sera against oncornaviruses and oncornavirus-associated antigens of human cultured cells]. / Poluchenie monospetsificheskikh syvorotok k onkornavirusam i assotsiirovannym s nimi antigenami perevivaemykh kletok cheloveka

ABSTRACT

A method for preparation of monospecific sera against oncornaviruses and oncornavirus-associated antigens of continouus human cells has been developed on the basis of the results of comparative studies of the properties of viral and virus-associated antigens of the cell. Utilization of an adsorbent from cells free of virus antigen for adsorption of immune sera against oncornaviruses with polyspecific properties resulted in preparation of specific antiviral serum free of antibody to virus-associated antigen of the cell. Sera against virus-associated antigens of the cell containing no antibody to virus were prepared by adsorption with concentrated purified virus isolated from the cell culture.