A common epitope of beta-lactoglobulin and serum retinol-binding proteins: elucidation of its core sequence using synthetic peptides.
Mol Immunol
; 29(4): 511-6, 1992 Apr.
Article
en En
| MEDLINE
| ID: mdl-1373468
ABSTRACT
One of the monoclonal antibodies raised against bovine beta-lactoglobulin reacted with human serum retinol binding protein. The finding that this monoclonal antibody also reacted with the serum retinol binding proteins isolated from other animals, suggested that this epitopic conformation is conserved among these proteins. Using ELISA and various synthetic peptides of defined sequence, we show in this paper that the epitope defined by this monoclonal antibody comprises of the highly conserved core sequence of DTDY present in beta-lactoglobulin and retinol binding proteins.
Search on Google
Banco de datos:
MEDLINE
Asunto principal:
Proteínas de Unión al Retinol
/
Lactoglobulinas
/
Epítopos
Límite:
Animals
/
Humans
Idioma:
En
Año:
1992
Tipo del documento:
Article