Comparison of the dynamics of resistance-associated mutations to nucleoside reverse transcriptase inhibitors, nonnucleoside reverse transcriptase inhibitors, and protease inhibitors after cessation of antiretroviral combination therapy.
Antimicrob Agents Chemother
; 48(2): 644-7, 2004 Feb.
Article
en En
| MEDLINE
| ID: mdl-14742228
ABSTRACT
The dynamics of mutations associated with resistance to antiretroviral drugs were analyzed after cessation of therapy. The results showed that the kinetics of the shift to wild-type amino acid residues were significantly faster for protease inhibitors, intermediate for nonnucleoside reverse transcriptase inhibitors, and slower for nucleoside reverse transcriptase inhibitors.
Texto completo:
1
Banco de datos:
MEDLINE
Asunto principal:
VIH-1
/
Inhibidores de la Proteasa del VIH
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Inhibidores de la Transcriptasa Inversa
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Fármacos Anti-VIH
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Terapia Antirretroviral Altamente Activa
/
Mutación
/
Nucleósidos
Tipo de estudio:
Observational_studies
/
Risk_factors_studies
Límite:
Humans
Idioma:
En
Año:
2004
Tipo del documento:
Article