No mutations in the GATA-1 gene detected in patients with acquired essential thrombocythemia.
Haematologica
; 89(5): 613-5, 2004 May.
Article
en En
| MEDLINE
| ID: mdl-15136229
ABSTRACT
Mutations in the GATA-1 gene have been identified in patients with familial macrothrombocytopenia and Down's syndrome patients with a transient myeloproliferative disorder and/or acute megakaryoblastic leukemia. We screened this gene in 46 patients with essential thrombocythemia and identified only a common single nucleotide polymorphism that is unlikely to be of pathological significance.
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Banco de datos:
MEDLINE
Asunto principal:
Factor de Transcripción GATA1
/
Trombocitemia Esencial
Tipo de estudio:
Prognostic_studies
Límite:
Animals
/
Female
/
Humans
Idioma:
En
Año:
2004
Tipo del documento:
Article