Thyroid hormone receptor subtypes and their interaction with steroid receptor coactivators.
Vitam Horm
; 68: 185-207, 2004.
Article
en En
| MEDLINE
| ID: mdl-15193455
ABSTRACT
Thyroid hormone (TH) is required for normal growth, development, and metabolism in metazoans. To influence this broad range of physiologic actions, TH is necessarily involved in the regulation of a multitude of genes in virtually every tissue. The diversity of gene expression regulation in response to TH is mediated through specific intranuclear TH receptors (TRs) and other nuclear coregulators. This chapter reviews TRs and nuclear coregulators, specifically coactivators, based on in vivo data from knockout (KO) mouse models.
Search on Google
Banco de datos:
MEDLINE
Asunto principal:
Hormonas Tiroideas
/
Factores de Transcripción
/
Receptores de Hormona Tiroidea
/
Transactivadores
/
Regulación de la Expresión Génica
Tipo de estudio:
Prognostic_studies
Límite:
Animals
/
Humans
Idioma:
En
Año:
2004
Tipo del documento:
Article