Serum hyperviscosity syndrome associated with multiple myeloma in two cats.
J Am Vet Med Assoc
; 200(1): 79-82, 1992 Jan 01.
Article
en En
| MEDLINE
| ID: mdl-1537697
ABSTRACT
Serum hyperviscosity syndrome was diagnosed in 2 cats with multiple myeloma. Clinical signs included pale mucous membranes, dehydration, retinal hemorrhages, dilated and tortuous retinal vessels, seizures, head-tilt, nystagmus, systolic murmur, and gallop rhythm. Laboratory abnormalities included hyperglobulinemia, azotemia, hyperphosphatemia, nonregenerative anemia, and thrombocytopenia. Both cats had IgG monoclonal gammopathy, Bence Jones proteinuria, increased numbers of bone marrow plasma cells, and high values for relative serum viscosity. Renal disease was suspected in both cats. Cardiac hypertrophy was documented in 1 cat and was suspected in the other cat. Chemotherapy, using melphalan, prednisone, and vincristine, caused short-term remission in both cats, and plasmapheresis was used to lower serum protein concentration in 1 cat. Serum hyperviscosity syndrome rarely develops in cats, but should be suspected when monoclonal gammopathy exists with signs of neurologic, cardiac, or retinal disease.
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Banco de datos:
MEDLINE
Asunto principal:
Viscosidad Sanguínea
/
Enfermedades de los Gatos
/
Mieloma Múltiple
Tipo de estudio:
Risk_factors_studies
Límite:
Animals
Idioma:
En
Año:
1992
Tipo del documento:
Article