Molecular cloning of toxins expressed by the venom gland of Lasiodora sp.

Vieira, A L G; Moura, M B; Babá, E H; Chávez-Olórtegui, C; Kalapothakis, E; Castro, I M

Vieira, A L G; Moura, M B; Babá, E H; Chávez-Olórtegui, C; Kalapothakis, E; Castro, I M.

Vieira AL; Laboratório de Biologia Celular e Molecular, Núcleo de Pesquisa em Ciências Biológicas, Universidade Federal de Ouro Preto, Campus do Morro do Cruzeiro, Ouro Preto, MG 35.400-00, Brazil.

Toxicon ; 44(8): 949-52, 2004 Dec 15.

Article en En | MEDLINE | ID: mdl-15530979

ABSTRACT

ABSTRACT

The present work describes the identification of toxins expressed by the venom gland of the spider Lasiodora sp. The toxins LTx1, LTx2 and LTx3 were identified by the screening of a cDNA library. These toxins showed significant similarity at the amino acid level with spider toxins from Lasiodora parahybana, Eurypelma californicum, Brachypelma smithii, Selenocosmia huwena.

Asunto(s)

Venenos de Araña/química; Arañas/química; Secuencia de Aminoácidos; Animales; Secuencia de Bases; Clonación Molecular; Expresión Génica; Datos de Secuencia Molecular; Alineación de Secuencia; Especificidad de la Especie

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Banco de datos: MEDLINE Asunto principal: Venenos de Araña / Arañas Tipo de estudio: Prognostic_studies Límite: Animals Idioma: En Año: 2004 Tipo del documento: Article

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