5-Amidinobenzo[b]thiophenes as dual inhibitors of factors IXa and Xa.
Bioorg Med Chem Lett
; 15(1): 29-35, 2005 Jan 03.
Article
en En
| MEDLINE
| ID: mdl-15582405
Syntheses and SAR studies of 5-amidinobenzo[b]thiophene analogs provided compounds with low submicromolar factor IXa activity and equal or slightly better selectivity relative to factor Xa.
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Banco de datos:
MEDLINE
Asunto principal:
Tiofenos
/
Factor IXa
/
Inhibidores de Serina Proteinasa
/
Inhibidores del Factor Xa
Idioma:
En
Año:
2005
Tipo del documento:
Article