Discovery of potent and selective phenylalanine based dipeptidyl peptidase IV inhibitors.

Xu, Jinyou; Wei, Lan; Mathvink, Robert; He, Jiafang; Park, You-Jung; He, Huaibing; Leiting, Barbara; Lyons, Kathryn A; Marsilio, Frank; Patel, Reshma A; Wu, Joseph K; Thornberry, Nancy A; Weber, Ann E

Xu, Jinyou; Wei, Lan; Mathvink, Robert; He, Jiafang; Park, You-Jung; He, Huaibing; Leiting, Barbara; Lyons, Kathryn A; Marsilio, Frank; Patel, Reshma A; Wu, Joseph K; Thornberry, Nancy A; Weber, Ann E.

Xu J; Department of Medicinal Chemistry, Merck & Co., Inc., PO Box 2000, Rahway, NJ 07065, USA.

Bioorg Med Chem Lett ; 15(10): 2533-6, 2005 May 16.

Article en En | MEDLINE | ID: mdl-15863311

Asunto(s)

Dipeptidil Peptidasa 4/efectos de los fármacos; Fenilalanina/farmacología; Inhibidores de Proteasas/farmacología; Fenilalanina/química; Inhibidores de Proteasas/química

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Banco de datos: MEDLINE Asunto principal: Fenilalanina / Inhibidores de Proteasas / Dipeptidil Peptidasa 4 Idioma: En Año: 2005 Tipo del documento: Article

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PubMed Links

Banco de datos: MEDLINE Asunto principal: Fenilalanina / Inhibidores de Proteasas / Dipeptidil Peptidasa 4 Idioma: En Año: 2005 Tipo del documento: Article