Effects of extremely low-frequency electromagnetic fields on morphine-induced conditioned place preferences in rats.
Neurosci Lett
; 390(2): 72-5, 2005 Dec 23.
Article
en En
| MEDLINE
| ID: mdl-16125316
ABSTRACT
In the present study, we examined the effects of extremely low-frequency (ELF) electromagnetic fields on morphine-induced conditioned place preferences in rats. During the conditioning phase (12 days), three groups of rats were placed in a sensory cue-defined environment paired with morphine (10mg/kg, i.p.) following exposure to either 20 Hz (1.80 mT) or 50 Hz (2.20 mT) or sham electromagnetic fields for 60 min/day, respectively, and were placed in another sensory cue-defined environment paired with physiological saline (1 ml/kg, i.p.) without exposure to electromagnetic fields. After finishing 12 days of conditioning, preference tests for the morphine-paired place were performed during a 10-day withdrawal period. The exposure to electromagnetic fields substantially potentiated morphine-induced place preferences in rodents, suggesting that ELF electromagnetic fields can increase the propensity for morphine-induced conditioned behaviors.
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Banco de datos:
MEDLINE
Asunto principal:
Conducta Animal
/
Condicionamiento Psicológico
/
Campos Electromagnéticos
/
Analgésicos Opioides
/
Morfina
Límite:
Animals
/
Humans
/
Male
Idioma:
En
Año:
2005
Tipo del documento:
Article