C3'-cis-Substituted carboxycyclopropyl glycines as metabotropic glutamate 2/3 receptor agonists: synthesis and SAR studies.
Bioorg Med Chem
; 13(23): 6556-70, 2005 Dec 01.
Article
en En
| MEDLINE
| ID: mdl-16153851
ABSTRACT
The synthesis of a series of C3'-cis-substituted carboxycyclopropyl glycines bearing a wide variety of functional groups is described, and the structure-activity relationship for this series as agonists of group II metabotropic glutamate receptors is reported.
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Banco de datos:
MEDLINE
Asunto principal:
Receptores de Glutamato Metabotrópico
/
Glicina
Límite:
Humans
Idioma:
En
Año:
2005
Tipo del documento:
Article