[Effect of glutamine and growth hormone on adaptation in short bowel syndrome].
Zhonghua Wei Chang Wai Ke Za Zhi
; 8(5): 429-31, 2005 Sep.
Article
en Zh
| MEDLINE
| ID: mdl-16224660
ABSTRACT
OBJECTIVE:
To assess the effects of parenteral glutamine and growth hormone supplementation on gut adaptation for patients with short bowel syndrome.METHODS:
Twenty-six patients [male 15, female 11, aged (39 +/- 23) years] with short bowel syndrome received parenteral nutrition (PN) 3-52 months after surgical resection. The median length of remnant small intestine was 42.5(0-100)cm. All patients received growth hormone (0.10+/- 0.06) mg.kg(-1).d(-1) plus glutamine (0.30 +/- 0.17) mg.kg(-1).d(-1) for two or three weeks.RESULTS:
Among the 26 patients, PN was not required soon after treatment in 34.6% (n=9) of the patients, the frequency and volume of PN decreased from (6.0 +/- 1.0) d to (4.2 +/- 1.0) d, from (13.6 +/- 5.2) L per week to (8.2 +/- 3.3) L per week respectively in 30.8% (n=8) of the patients,while 34.6% (n=9) still required PN after treatment.CONCLUSION:
The combined administration of glutamine and growth hormone can promote remnant intestinal adaptation in short bowel patients.
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Banco de datos:
MEDLINE
Asunto principal:
Síndrome del Intestino Corto
/
Hormona del Crecimiento
/
Nutrición Parenteral
/
Glutamina
Límite:
Adolescent
/
Adult
/
Child
/
Female
/
Humans
/
Male
/
Middle aged
Idioma:
Zh
Año:
2005
Tipo del documento:
Article