Activity of nitric oxide synthase and concentration of nitric oxide end metabolites in the gingiva under experimental pathological conditions.
Bull Exp Biol Med
; 140(4): 391-3, 2005 Oct.
Article
en En
| MEDLINE
| ID: mdl-16671561
ABSTRACT
Parameters of NO metabolism in the gingiva were studied during experimental periodontitis accompanied by alloxan diabetes and exogenous hypercholesterolemia. We measured activities of inducible and constitutive NO synthase and concentrations of stable NO end metabolites in rat gingival tissue (total contents of nitrite and nitrate). Under pathological conditions NO-metabolism significantly differed from the control. Treatment with mexidol for 14 days significantly decreased activity of inducible NO synthase in the gingiva of experimental animals.
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Banco de datos:
MEDLINE
Asunto principal:
Periodontitis
/
Óxido Nítrico Sintasa de Tipo II
/
Óxido Nítrico Sintasa de Tipo III
/
Encía
/
Óxido Nítrico
Límite:
Animals
Idioma:
En
Año:
2005
Tipo del documento:
Article