Liver transplantation for cirrhosis in cystic fibrosis.
Can J Gastroenterol
; 20(7): 475-8, 2006 Jul.
Article
en En
| MEDLINE
| ID: mdl-16858500
ABSTRACT
BACKGROUND:
Liver disease is the third most common cause of death in children with cystic fibrosis (CF). Liver transplantation is an effective treatment in children with hepatic failure.AIMS:
The objective of the present study was to review the indications and postoperative course of hepatic transplantation in a cystic fibrosis population. PATIENTS Five children with CF, at a mean age of 16.5 years, underwent liver transplantation.RESULTS:
All patients showed cirrhosis, portal hypertension and hepatic failure. The main postoperative complication was ascites refractory to treatment in two patients. No significant deterioration of the pulmonary function was noted. Two patients died, one of Hodgkin lymphoma and the other of progressive pulmonary failure.CONCLUSION:
Liver transplantation was indicated in children with CF when hepatic failure and/or severe portal hypertension was present with well-preserved pulmonary function.
Texto completo:
1
Banco de datos:
MEDLINE
Asunto principal:
Trasplante de Hígado
/
Fibrosis Quística
/
Cirrosis Hepática
Tipo de estudio:
Etiology_studies
Límite:
Female
/
Humans
/
Infant
/
Male
/
Newborn
Idioma:
En
Año:
2006
Tipo del documento:
Article