Peripartum cardiomyopathy.
Int J Gynaecol Obstet
; 95(2): 104-9, 2006 Nov.
Article
en En
| MEDLINE
| ID: mdl-16935289
ABSTRACT
OBJECTIVE:
To determine the clinical and echocardiographic profiles of women with peripartum cardiomyopathy and ascertain the natural course of the disease.METHODS:
Fifty-six women with peripartum cardiomyopathy were followed up for a mean period of 6.1 years and their clinical and echocardiographic profiles were studied as well as their outcomes.RESULTS:
The mean+/-SD age at presentation was 31+/-5 years and mean parity was 2.6+/-1. Of the 56 patients, 18 (32.1%) had NYHA Class II, 24 (42.9%) had NYHA Class III, and 14 (25%) had NYHA Class IV symptoms, and 21 (37.5%) and 35 (62.5%), respectively, presented with features of heart failure during pregnancy and the postpartum. During follow-up, the left ventricular ejection fraction improved from 31%+/-7.2% to 43%+/-8% (P=0.05). Nine patients (16.1%) became pregnant, with a mortality of 55.5% during pregnancy and 23.2% during follow-up.CONCLUSION:
Women with peripartum cardiomyopathy present with severe left ventricular dysfunction late in the pregnancy or early in the puerperium. A considerable number of women still die from this condition despite the use of angiotensin-converting enzyme inhibitors and beta-blockers. A subsequent pregnancy carries a very high risk of mortality.
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Banco de datos:
MEDLINE
Asunto principal:
Complicaciones Cardiovasculares del Embarazo
/
Disfunción Ventricular Izquierda
/
Insuficiencia Cardíaca
/
Cardiomiopatías
Tipo de estudio:
Observational_studies
/
Prognostic_studies
/
Risk_factors_studies
Límite:
Adult
/
Female
/
Humans
/
Pregnancy
País como asunto:
Asia
Idioma:
En
Año:
2006
Tipo del documento:
Article