A study of immunoglobulin-containing and other cells in ovine aural squamous cell carcinoma.
J Comp Pathol
; 103(2): 221-8, 1990 Aug.
Article
en En
| MEDLINE
| ID: mdl-1700985
ABSTRACT
The peroxidase-antiperoxidase method was used to quantify immunoglobulin (Ig)-containing cells at the host-tumour interface in ovine aural squamous cell carcinoma lesions at various stages of development. IgM-containing cells were never observed; only scattered, but strongly staining, IgA-containing cells were present. IgG-containing cells predominated; their prevalence increased from 0.17 +/- 0.34 cells per high power field (hpf; mean +/- standard deviation) in precursor lesions to a maximum of 13.6 +/- 2.6 cells per hpf in overt tumours which had not metastasized. Their prevalence in overt tumours which had metastasized was 4.6 +/- 3.9 cells per hpf. Quantitation of pyroninophils in sections stained by the methyl green-pyronin method showed a greater prevalence of plasma cells than IgG-containing cells, but a similar pattern of change was apparent. Mast cells were most prevalent in early stages, but no significant change in eosinophil numbers was observed.
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Banco de datos:
MEDLINE
Asunto principal:
Enfermedades de las Ovejas
/
Inmunoglobulinas
/
Neoplasias del Oído
/
Carcinoma de Células Escamosas
Tipo de estudio:
Risk_factors_studies
Límite:
Animals
Idioma:
En
Año:
1990
Tipo del documento:
Article