Antibodies that impair insulin receptor binding in an unusual diabetic syndrome with severe insulin resistance.
Science
; 190(4209): 63-5, 1975 Oct 03.
Article
en En
| MEDLINE
| ID: mdl-170678
ABSTRACT
Six patients with a unique form of diabetes associated with extreme insulin resistance have markedly reduced insulin binding to specific receptors on their circulating monocytes. When normal insulin receptors were exposed to serum or immunoglobulin fractions from three of these patients in vitro the specific binding defect was reproduced.
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Banco de datos:
MEDLINE
Asunto principal:
Autoanticuerpos
/
Resistencia a la Insulina
/
Receptores de Superficie Celular
/
Diabetes Mellitus
/
Insulina
Límite:
Animals
/
Female
/
Humans
Idioma:
En
Año:
1975
Tipo del documento:
Article