Successful treatment of myelodysplastic syndrome-induced pyoderma gangrenosum.
Neth J Med
; 64(11): 422-4, 2006 Dec.
Article
en En
| MEDLINE
| ID: mdl-17179573
ABSTRACT
We report successful treatment of a refractory myelodysplastic syndrome-associated pyoderma gangrenosum with the combination of thalidomide and interferon-alpha2a in a single patient. A non-healing wound developed on a 40-year-old woman's left thumb after minor trauma. Massive ulcerovegetative lesions developed after reconstruction surgery. Histopathological examination of the bone marrow and cytogenetic studies revealed an atypical myeloproliferative/myelodysplastic syndrome. The skin lesions resolved dramatically after two months of thalidomide and interferon-alpha2a combination therapy and the haematological status improved.
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Banco de datos:
MEDLINE
Asunto principal:
Talidomida
/
Síndromes Mielodisplásicos
/
Interferón-alfa
/
Piodermia Gangrenosa
Límite:
Adult
/
Female
/
Humans
Idioma:
En
Año:
2006
Tipo del documento:
Article