High accuracy multiple scatter modelling for 3D whole body PET.
Phys Med Biol
; 52(3): 829-47, 2007 Feb 07.
Article
en En
| MEDLINE
| ID: mdl-17228124
ABSTRACT
A new technique for modelling multiple-order Compton scatter which uses the absolute probabilities relating the image space to the projection space in 3D whole body PET is presented. The details considered in this work give a valuable insight into the scatter problem, particularly for multiple scatter. Such modelling is advantageous for large attenuating media where scatter is a dominant component of the measured data, and where multiple scatter may dominate the total scatter depending on the energy threshold and object size. The model offers distinct features setting it apart from previous research (1) specification of the scatter distribution for each voxel based on the transmission data, the physics of Compton scattering and the specification of a given PET system; (2) independence from the true activity distribution; (3) in principle no scaling or iterative process is required to find the distribution; (4) explicit multiple scatter modelling; (5) no scatter subtraction or addition to the forward model when included in the system matrix used with statistical image reconstruction methods; (6) adaptability to many different scatter compensation methods from simple and fast to more sophisticated and therefore slower methods; (7) accuracy equivalent to that of a Monte Carlo model. The scatter model has been validated using Monte Carlo simulation (SimSET).
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Banco de datos:
MEDLINE
Asunto principal:
Tomografía de Emisión de Positrones
Tipo de estudio:
Health_economic_evaluation
Límite:
Humans
Idioma:
En
Año:
2007
Tipo del documento:
Article