Overcoming tumor drug resistance with high-affinity taxanes: a SAR study of C2-modified 7-acyl-10-deacetyl cephalomannines.

Yang, Chun-Gang; Barasoain, Isabel; Li, Xuan; Matesanz, Ruth; Liu, Ronghua; Sharom, Frances J; Yin, Da-Li; Díaz, J Fernando; Fang, Wei-Shuo

Yang, Chun-Gang; Barasoain, Isabel; Li, Xuan; Matesanz, Ruth; Liu, Ronghua; Sharom, Frances J; Yin, Da-Li; Díaz, J Fernando; Fang, Wei-Shuo.

Yang CG; Department of Medicinal Chemistry, Institute of Materia Medica, Chinese Academy of Medical Sciences, 1 Xian Nong Tan Street, Beijing 100050, China.

ChemMedChem ; 2(5): 691-701, 2007 May.

Article en En | MEDLINE | ID: mdl-17385753

Asunto(s)

Mananos/química; Mananos/farmacología; Taxoides/farmacología; Línea Celular Tumoral; Resistencia a Antineoplásicos; Humanos; Estructura Molecular; Relación Estructura-Actividad; Taxoides/química

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