False-positive beta-human chorionic gonadotropin values in the follow-up of gestational trophoblastic disease.
Clin Transl Oncol
; 9(5): 332-4, 2007 May.
Article
en En
| MEDLINE
| ID: mdl-17525045
ABSTRACT
Gestational trophoblastic disease consists of a pathological spectrum of entities from molar pregnancies, which are premalignant conditions, to malignant invasive choriocarcinoma. Serum Beta-human chorionic gonadotropin (hCG) levels are essential both in the diagnosis and in the follow-up. There are high rates of complete responses and long-term survivors, because of the excellent chemosensitivity of these tumours. After initial management, an increased level of Beta-hCG indicates persistent disease. However, in the absence of evidence of persistent disease, false-positive Beta-hCG values may be considered. We present here the case of a woman with a metastatic choriocarcinoma in complete response after chemotherapy, who developed later persistent false-positive values of Beta-hCG in the follow-up. Causes of false-positive Beta-hCG determinations are revised.
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Banco de datos:
MEDLINE
Asunto principal:
Gonadotropina Coriónica Humana de Subunidad beta
/
Enfermedad Trofoblástica Gestacional
Tipo de estudio:
Observational_studies
/
Prognostic_studies
Límite:
Adult
/
Female
/
Humans
/
Pregnancy
Idioma:
En
Año:
2007
Tipo del documento:
Article