Highly efficient asymmetric reduction of arylpropionic aldehydes by horse liver alcohol dehydrogenase through dynamic kinetic resolution.
Chem Commun (Camb)
; (39): 4038-40, 2007 Oct 21.
Article
en En
| MEDLINE
| ID: mdl-17912408
ABSTRACT
The enantioselective synthesis of (2S)-2-phenylpropanol and (2S)-2-(4-iso-butylphenyl)propanol ((S)-Ibuprofenol) has been achieved by means of Horse Liver Alcohol Dehydrogenase (HLADH) in buffered aqueous solution or buffered organic solvent mixtures; under the reaction conditions, a dynamic kinetic resolution (DKR) process was realized with good reaction yields and enantiomeric ratios.
Search on Google
Banco de datos:
MEDLINE
Asunto principal:
Propionatos
/
Alcohol Deshidrogenasa
/
Aldehídos
/
Hígado
Límite:
Animals
Idioma:
En
Año:
2007
Tipo del documento:
Article