Progress toward the synthesis of nonionic oligonucleotide analogues with sulfonate and sulfonamide internucleotide linkages.

Secrist, J A; Crooks, P A; Maddry, J A; Reynolds, R C; Rathore, A S; Ahktar, M S; Montgomery, J A

Secrist, J A; Crooks, P A; Maddry, J A; Reynolds, R C; Rathore, A S; Ahktar, M S; Montgomery, J A.

Secrist JA; Organic Chemistry Department, Southern Research Institute, Birmingham, AL 35255-5305.

Nucleic Acids Symp Ser ; (24): 5-8, 1991.

Article en En | MEDLINE | ID: mdl-1841378

RESUMEN

The synthesis of building blocks for the preparation of nonionic oligonucleotide analogues with sulfonate and sulfonamide internucleotide linkages is described. Coupling conditions for the conversion of several of these monomers to dimers are also described.

Asunto(s)

Fosfatos de Dinucleósidos/síntesis química; Oligonucleótidos/síntesis química; Sulfonamidas; Ácidos Sulfónicos; Tionucleótidos; Indicadores y Reactivos; Estructura Molecular

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Banco de datos: MEDLINE Asunto principal: Oligonucleótidos / Sulfonamidas / Ácidos Sulfónicos / Tionucleótidos / Fosfatos de Dinucleósidos Idioma: En Año: 1991 Tipo del documento: Article

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