[The relation between post-acute coronary syndrome anxiety and serum levels of inflammatory factors].
Zhonghua Nei Ke Za Zhi
; 46(12): 1022-4, 2007 Dec.
Article
en Zh
| MEDLINE
| ID: mdl-18478922
ABSTRACT
OBJECTIVE:
To explore the role of inflammatory factors (interleukin-6, tumor necrosis factor alpha, high sensitive C reactive protein) in the pathogenesis of anxiety after acute coronary syndrome (ACS) by investigating the serum levels of interleukin-6 (IL-6), tumor necrosis factor alpha (TNFalpha) and high sensitive C reactive protein (hsCRP).METHODS:
Serum IL-6, TNFalpha and hsCRP levels were measured in 105 ACS patients within 7 days after onset of the event. Symptoms of anxiety were evaluated by self-reporting standardized questionnaire, using a validated Chinese version of Hospital Anxiety and Depression Scale (HADS-A)-Anxiety Subscale (7 items) within 72 hours of the event. Demographic and clinical data including cardiac risk factors were recorded.RESULTS:
The median of TNFalpha was lower in the anxious patients with ACS than that of non-anxious ones (44.55 vs 61.70, P = 0.004). Neither the levels of hsCRP nor the levels of IL-6 were found to be different between the groups with anxiety and without.CONCLUSION:
Anxiety after ACS does not increase the inflammatory reaction in the ACS patients.
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Banco de datos:
MEDLINE
Asunto principal:
Ansiedad
/
Mediadores de Inflamación
/
Síndrome Coronario Agudo
Tipo de estudio:
Etiology_studies
/
Risk_factors_studies
Límite:
Aged
/
Female
/
Humans
/
Male
/
Middle aged
Idioma:
Zh
Año:
2007
Tipo del documento:
Article