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Opa1-mediated cristae opening is Bax/Bak and BH3 dependent, required for apoptosis, and independent of Bak oligomerization.
Yamaguchi, Ryuji; Lartigue, Lydia; Perkins, Guy; Scott, Ray T; Dixit, Amruta; Kushnareva, Yulia; Kuwana, Tomomi; Ellisman, Mark H; Newmeyer, Donald D.
  • Yamaguchi R; La Jolla Institute for Allergy and Immunology, 9420 Athena Circle, La Jolla, CA 92037, USA.
  • Lartigue L; La Jolla Institute for Allergy and Immunology, 9420 Athena Circle, La Jolla, CA 92037, USA.
  • Perkins G; Department of Neurosciences and National Center for Microscopy and Imaging Research, University of California, San Diego, La Jolla, CA 92093, USA.
  • Scott RT; Department of Neurosciences and National Center for Microscopy and Imaging Research, University of California, San Diego, La Jolla, CA 92093, USA.
  • Dixit A; Department of Neurosciences and National Center for Microscopy and Imaging Research, University of California, San Diego, La Jolla, CA 92093, USA.
  • Kushnareva Y; La Jolla Institute for Allergy and Immunology, 9420 Athena Circle, La Jolla, CA 92037, USA.
  • Kuwana T; Department of Pathology, Roy J. and Lucille A. Carver College of Medicine, University of Iowa, Iowa City, IA 52242, USA.
  • Ellisman MH; Department of Neurosciences and National Center for Microscopy and Imaging Research, University of California, San Diego, La Jolla, CA 92093, USA.
  • Newmeyer DD; La Jolla Institute for Allergy and Immunology, 9420 Athena Circle, La Jolla, CA 92037, USA. Electronic address: don@liai.org.
Mol Cell ; 31(4): 557-569, 2008 Aug 22.
Article en En | MEDLINE | ID: mdl-18691924
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Texto completo: 1 Banco de datos: MEDLINE Asunto principal: Mitocondrias Hepáticas / Proteínas Proto-Oncogénicas / Apoptosis / Proteínas Reguladoras de la Apoptosis / Proteína X Asociada a bcl-2 / Proteína Destructora del Antagonista Homólogo bcl-2 / Proteína Proapoptótica que Interacciona Mediante Dominios BH3 / GTP Fosfohidrolasas / Proteínas de la Membrana Límite: Animals / Humans Idioma: En Año: 2008 Tipo del documento: Article
Texto completo
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Texto completo: 1 Banco de datos: MEDLINE Asunto principal: Mitocondrias Hepáticas / Proteínas Proto-Oncogénicas / Apoptosis / Proteínas Reguladoras de la Apoptosis / Proteína X Asociada a bcl-2 / Proteína Destructora del Antagonista Homólogo bcl-2 / Proteína Proapoptótica que Interacciona Mediante Dominios BH3 / GTP Fosfohidrolasas / Proteínas de la Membrana Límite: Animals / Humans Idioma: En Año: 2008 Tipo del documento: Article