Antipyretic and antiviral action of vitamin A in Moloney sarcoma virus- and poxvirus-inoculated mice.
J Natl Cancer Inst
; 57(2): 355-9, 1976 Aug.
Article
en En
| MEDLINE
| ID: mdl-187770
ABSTRACT
Six week-old male CBA/J mice fed a commercial powdered laboratory chow or the same chow supplemented with vitamin A palmitate (150,000 U/kg) were inoculated with either the Moloney strain of murine sarcoma virus (M-MuSV) or poxvirus. Central body temperature was measured daily. Both viruses elicited fevers, but the fevers were less pronounced and of shorter duration in the mice ingesting the vitamin A-supplemented diet. Palpable M-MuSV-induced tumors appeared later, were less frequent, grew more slowly, and were resorbed sooner in the mice fed the vitamin A supplement. Similarly, in these mice the appearance of pox lesions was delayed, their numbers reduced, and their disappearance hastened.
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Banco de datos:
MEDLINE
Asunto principal:
Sarcoma Experimental
/
Vitamina A
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Infecciones por Poxviridae
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Fiebre
Límite:
Animals
Idioma:
En
Año:
1976
Tipo del documento:
Article