ACR Appropriateness Criteria on Hodgkin's lymphoma: favorable prognosis stage I and II.
J Am Coll Radiol
; 5(10): 1054-66, 2008 Oct.
Article
en En
| MEDLINE
| ID: mdl-18812149
ABSTRACT
The treatment for favorable-prognosis stage I and II Hodgkin's lymphoma has evolved over the past several years. Studies have attempted to reduce long-term treatment-related side effects, such as second malignancies and cardiac toxicity, through reduced chemotherapy or reduced radiotherapy. Randomized trials have compared radiation therapy alone with combined-modality therapy (chemotherapy followed by involved-field radiotherapy). Recent and ongoing trials have evaluated the optimal regimen and number of cycles of chemotherapy and the optimal radiotherapy dose and field size as part of combined-modality therapy, as well as the elimination of radiation therapy. Combined-modality therapy represents the current standard of care for most patients with favorable-prognosis early-stage Hodgkin's lymphoma. Chemotherapy alone could also be an option for selected patients who are at low risk for relapse and high risk for late effects from radiotherapy. This article reviews recent and ongoing studies on treatment for favorable-prognosis early stage Hodgkin's lymphoma. Representative clinical cases are presented, with treatment recommendations from an expert panel of radiation oncologists and medical oncologists.
Texto completo:
1
Banco de datos:
MEDLINE
Asunto principal:
Radiología
/
Enfermedad de Hodgkin
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Ensayos Clínicos como Asunto
/
Guías de Práctica Clínica como Asunto
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Atención a la Salud
Tipo de estudio:
Clinical_trials
/
Guideline
/
Prognostic_studies
Límite:
Humans
País como asunto:
America do norte
Idioma:
En
Año:
2008
Tipo del documento:
Article