[Pharmacoeconomic results of introducing antimicrobial prophylaxis in surgery at a university hospital]. / Resultados farmacoeconómicos de una intervención para implantar un programa de profilaxis antibiótica quirúrgica en un hospital universitario.
Cir Esp
; 84(6): 333-6, 2008 Dec.
Article
en Es
| MEDLINE
| ID: mdl-19087780
ABSTRACT
OBJECTIVES:
The introduction of antimicrobial prophylaxis in surgery was designed and pre-intervention (controls) and post-intervention (cases) evaluations were carried out at a university tertiary hospital. PATIENTS ANDMETHOD:
Prospective recording of information on prophylaxis in all patients undergoing non-emergency abdominal surgery was analysed during a 3-week period before and after implementing an antimicrobial prophylaxis program. Adequacy of prophylaxis was defined as prescription of antibiotics (type, dose and duration of treatment) according to the Guidelines.RESULTS:
In the pre-intervention study included 36 patients; prophylaxis was inadequate in all patients (long-term in 22 cases; antibiotic class and long-term in 2 cases; antibiotic class, dose and long-term in 12 cases); mean duration of prophylaxis was 6 days (range 1 to 10 days); mean antibiotic cost per patient was 77 euro (range 9 to 412 euro); overall antibiotic cost for the 36 patients was 2770 euro. In the post-intervention study included 37 patients prophylaxis was inadequate in 11 patients (long-term in 10 cases; antibiotic class and long-term in 1 case); mean duration of prophylaxis was 2 days (range 1 to 9 days); mean antibiotic cost per patient was 16 euro (range 2 to 78 euro); overall antibiotic cost for the 37 patients was 593 euro. In the pre-intervention period antibiotic cost was 38 times higher than expected. In the post-intervention period it was 1.6 times higher than expected.CONCLUSIONS:
The most common reason of prophylaxis inadequacy is prolonged antibiotic treatment. A multidisciplinary intervention that comprises infectious diseases, surgical and pharmacy departments improves prophylaxis prescribing practice and avoids erroneous prescribing of antibiotics with both microbiological and economical cost savings.
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Banco de datos:
MEDLINE
Asunto principal:
Profilaxis Antibiótica
/
Adhesión a Directriz
/
Quimioterapia
/
Procedimientos Quirúrgicos Cardíacos
/
Antibacterianos
Tipo de estudio:
Guideline
Límite:
Humans
País como asunto:
Europa
Idioma:
Es
Año:
2008
Tipo del documento:
Article