Lymphoepithelioma-like carcinoma of the uterine cervix.
Arch Gynecol Obstet
; 280(5): 725-7, 2009 Nov.
Article
en En
| MEDLINE
| ID: mdl-19238413
ABSTRACT
PURPOSE:
To elucidate the clinicopathologic features of lymphoepithelioma-like carcinoma (LELC) of the uterine cervix, we examined three Japanese cases.METHODS:
We collected three cases of LELC of the uterine cervix between 2000 and 2007. We examined these patients' clinicopathologic data, Epstein-Barr virus (EBV) and human papilloma virus (HPV) infectious status, and infiltrated lymphocyte population.RESULTS:
Our patients had disease Fédération Internatinale de Gynécologie et d'Obstétrique stages I and II. All of them were free of disease at the time of the study. Macroscopically, one of the three tumors was polypoid. All tumor cells were negative for EBV and HPV using in situ hybridization and immunohistochemistry. The inflammatory background contained many CD3(+) and CD8(+) cells, but there were few CD4(+), CD20(+), or CD79a(+) cells.CONCLUSIONS:
In our Japanese series, LELC of the uterine cervix showed good prognosis, and there is no relationship between this carcinoma and EBV or HPV infection.
Texto completo:
1
Banco de datos:
MEDLINE
Asunto principal:
Carcinoma
/
Neoplasias del Cuello Uterino
Límite:
Adult
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Aged
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Female
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Humans
Idioma:
En
Año:
2009
Tipo del documento:
Article