[An azidomethyl protective group in the synthesis of oligoribonucleotides by the phosphotriester method].
Bioorg Khim
; 35(2): 270-3, 2009.
Article
en Ru
| MEDLINE
| ID: mdl-19537179
A rapid and effective method of an automatic oligoribonucleotide synthesis alternative to the phosphoroamidite one was developed based on the phosphotriester approach of internucleotide bond formation under intramolecular O-nucleophilic catalysis and the use of an azidomethyl group for protection of a nucleotide 2'-hydroxyl function.
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Banco de datos:
MEDLINE
Asunto principal:
Oligorribonucleótidos
Idioma:
Ru
Año:
2009
Tipo del documento:
Article