Complete genome sequence of a virulent Newcastle disease virus isolated from an outbreak in chickens in Egypt.
Virus Genes
; 39(2): 234-7, 2009 Oct.
Article
en En
| MEDLINE
| ID: mdl-19590944
ABSTRACT
The complete genome sequence of a virulent Newcastle disease virus (NDV) isolated from chickens in Egypt was determined and compared to the sequence of NDV strains isolated from different parts of the world. The genome is 15,186 nucleotides (nt) long and consists of 6 genes in the order of 3'-N-P-M-F-HN-L-5'. The genome contains a 55-nt leader region at the 3' end and a 114-nt trailer region at the 5' end. Interestingly, the phylogenetic analysis showed that strain Egypt is closely related with the NDV strains isolated in China. In addition, the sequence of the fusion protein cleavage site of strain Egypt was identical to that of the NDV strain recently isolated in Mali. Determination of complete genome sequences of additional NDV strains from Africa is necessary to understand the epidemiology of currently circulating viruses in Africa.
Texto completo:
1
Banco de datos:
MEDLINE
Asunto principal:
Enfermedades de las Aves de Corral
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Virus de la Enfermedad de Newcastle
/
Brotes de Enfermedades
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Genoma Viral
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Análisis de Secuencia de ADN
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Enfermedad de Newcastle
Límite:
Animals
País como asunto:
Africa
Idioma:
En
Año:
2009
Tipo del documento:
Article