Synthesis of fluorinated allenes via palladium-catalyzed monofluoromethylation using FBSM.

Ogasawara, Masamichi; Murakami, Hidetoshi; Furukawa, Tatsuya; Takahashi, Tamotsu; Shibata, Norio

Ogasawara, Masamichi; Murakami, Hidetoshi; Furukawa, Tatsuya; Takahashi, Tamotsu; Shibata, Norio.

Ogasawara M; Catalysis Research Center and Graduate School of Life Science, Hokkaido University, Kita-ku, Sapporo 001-0021, Japan. ogasawar@cat.hokudai.ac.jp

Chem Commun (Camb) ; (47): 7366-8, 2009 Dec 21.

Article en En | MEDLINE | ID: mdl-20024230

ABSTRACT

ABSTRACT

Palladium-catalyzed monofluoromethylation of substituted 2-bromo-1,3-dienes using fluorobis(phenylsulfonyl)methane (FBSM) as a pronucleophile gave previously unknown monofluoromethylated allenes in high yields, which are the isosteres of biologically attractive allenic alcohols.

Asunto(s)

Alcadienos/síntesis química; Flúor/química; Hidrocarburos Fluorados/química; Metano/análogos & derivados; Paladio/química; Compuestos de Bromina/química; Catálisis; Metano/química; Metilación; Estructura Molecular

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Texto completo: 1 Banco de datos: MEDLINE Asunto principal: Paladio / Alcadienos / Flúor / Hidrocarburos Fluorados / Metano Idioma: En Año: 2009 Tipo del documento: Article

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Texto completo: 1 Banco de datos: MEDLINE Asunto principal: Paladio / Alcadienos / Flúor / Hidrocarburos Fluorados / Metano Idioma: En Año: 2009 Tipo del documento: Article