Delay correction for the assessment of blood-brain barrier permeability using first-pass dynamic perfusion CT.
AJNR Am J Neuroradiol
; 32(7): E134-8, 2011 Aug.
Article
en En
| MEDLINE
| ID: mdl-20538824
ABSTRACT
SUMMARY:
Hemorrhagic transformation is a serious potential complication of ischemic stroke with damage to the BBB as one of the contributing mechanisms. BBB permeability measurements extracted from PCT by using the Patlak model can provide a valuable assessment of the extent of BBB damage. Unfortunately, Patlak assumptions require extended PCT acquisition, increasing the risk of motion artifacts. A necessary correction is presented for obtaining accurate BBB permeability measurements from first-pass PCT.
Texto completo:
1
Banco de datos:
MEDLINE
Asunto principal:
Barrera Hematoencefálica
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Tomografía Computarizada por Rayos X
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Isquemia Encefálica
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Accidente Cerebrovascular
Tipo de estudio:
Observational_studies
/
Prognostic_studies
/
Risk_factors_studies
Límite:
Adult
/
Aged
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Aged80
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Female
/
Humans
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Male
/
Middle aged
Idioma:
En
Año:
2011
Tipo del documento:
Article