Bilateral ovarian gonadoblastoma with coexisting dysgerminoma in a girl with 46, XX karyotype.
J Obstet Gynaecol Res
; 36(3): 697-700, 2010 Jun.
Article
en En
| MEDLINE
| ID: mdl-20598061
ABSTRACT
Gonadoblastoma is a rare gonadal tumor with tumor cells arranged in nests surrounded by ovarian stroma containing Leydig or lutein-type cells. In 50% of the cases, there is an overgrowth of germ cells with progression to dysgerminoma. A case of gonadoblastoma with coexisting dysgerminoma developing in both ovaries of a 20-year-old girl who had increased abdominal girth is presented here. A pelvic mass measuring 20 x 14 cm was detected by pelvic ultrasonography. Bilateral salphingo-oophorectomy was performed. The histopathological report revealed bilateral gonadoblastoma with coexisting dysgerminoma. After surgery the patient received radiation and chemotherapy (BEP bleomycin, etoposide, cisplatin) and was started on hormone replacement therapy. Five years and eight months after treatment, the patient is well and free of recurrence.
Texto completo:
1
Banco de datos:
MEDLINE
Asunto principal:
Neoplasias Ováricas
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Gonadoblastoma
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Disgerminoma
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Neoplasias Primarias Múltiples
Límite:
Adult
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Female
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Humans
Idioma:
En
Año:
2010
Tipo del documento:
Article