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The new Powerplex® ESX17 and ESI17 kits in paternity and maternity analyses involving people from Africa--including allele frequencies for three African populations.
Poetsch, Micaela; Ergin, Zeynep; Bayer, Katharina; El-Mostaqim, Daniela; Rakotomavo, Noel; Browne, Edmund N L; Timmann, Christian; Horstmann, Rolf D; Schwark, Thorsten; von Wurmb-Schwark, Nicole.
  • Poetsch M; Institute of Legal Medicine, University Hospital Essen, Hufelandstr. 55, 45122, Essen, Germany. micaela.poetsch@uk-essen.de
Int J Legal Med ; 125(1): 149-54, 2011 Jan.
Article en En | MEDLINE | ID: mdl-20827485
ABSTRACT
Paternity and maternity investigations in immigration procedures are frequently done in Germany. Since mostly only one parent and one or more children are investigated, the occurrence of possible mutational events has to be interpreted with great care and the analysis of as many STRs as possible is recommended. The new Powerplex® ESX17 and Powerplex® ESI17 kits from Promega comprising both eleven established STRs and additionally the loci D1S1656, D2S441, D10S1248, D12S391, and D22S1045 (in different order) are potential tools in such paternity or maternity analyses, but only few allele frequency data for the five new loci exist. Here, we provide allele frequencies for the five additional STRs from three different populations from Africa. In addition, we present two maternity cases and one paternity case in which a clear inclusion or exclusion of the alleged parent could only be achieved by the additional application of the new Powerplex® ESX17 kit.
Asunto(s)

Texto completo: 1 Banco de datos: MEDLINE Asunto principal: Paternidad / Frecuencia de los Genes / Genética de Población Límite: Adolescent / Adult / Aged / Female / Humans / Male / Middle aged País como asunto: Africa Idioma: En Año: 2011 Tipo del documento: Article

Texto completo: 1 Banco de datos: MEDLINE Asunto principal: Paternidad / Frecuencia de los Genes / Genética de Población Límite: Adolescent / Adult / Aged / Female / Humans / Male / Middle aged País como asunto: Africa Idioma: En Año: 2011 Tipo del documento: Article