[Modern Helicobacter pylori therapies in times of increasing anti biotic resistance]. / Moderne Helicobacter-pylori-Therapien in Zeiten zunehmender Antibiotikaresistenz.
Med Klin (Munich)
; 105(11): 787-91, 2010 Nov.
Article
en De
| MEDLINE
| ID: mdl-21136236
ABSTRACT
Recommendation for the diagnosis and treatment of Helicobacter pylori Infection are defined in recent national and international guidelines. In Germany, proton pump inhibitor-based triple therapy with clarithromycin and metronidazole or amoxicillin is still the standard in first line therapy. However, success rates have decreased substantially during the last years due to increasing antibiotic resistance, particularly in patients from Southern Europe. In addition, antimicrobial resistance rates against the standard antibiotics further increases dramatically after failure of first line therapy deeming the repeated use of these antibiotics basically impossible. Against this background, a critical appraisal and eventually adaption of therapeutic options both in first line and rescue treatment appears necessary. This paper gives an overview on the current status of therapeutic options and developments in the treatment of H. pylori infection in the light of increasing antibiotic resistance.
Texto completo:
1
Banco de datos:
MEDLINE
Asunto principal:
Helicobacter pylori
/
Infecciones por Helicobacter
/
Claritromicina
/
Farmacorresistencia Bacteriana Múltiple
/
Inhibidores de la Bomba de Protones
/
Amoxicilina
/
Metronidazol
/
Antiulcerosos
/
Antibacterianos
Tipo de estudio:
Diagnostic_studies
/
Guideline
Límite:
Humans
País como asunto:
Europa
Idioma:
De
Año:
2010
Tipo del documento:
Article