[Epidemiology of parasitic diseases, hypereosinophilia, IgE from tropical and European parasitological origins]. / Epidémiologie des parasitoses, hyperéosinophilies sanguines et IgE d'origines parasitaires en milieux tempérés et tropicaux.
Bull Acad Natl Med
; 194(3): 561-2; discussion 562-4, 2010 Mar.
Article
en Fr
| MEDLINE
| ID: mdl-21171249
ABSTRACT
Etiologic investigations of hypereosinophilia, often accompanied by IgE elevation, depends on the patient's geographic origin and travel history. In France, helminth diseases are the only parasitoses associated with hypereosinophilia. Some, such as oxyurosis in children, are frequent but generally mild. More severe but less frequent infections include distomatoses, trichinellosis, taeniasis, echinococcosis and visceral larva migrans. Among subjects originating from or having travelled to tropical areas with poor hygiene, eosinophilia may be due to early intense polyparasitism and has little etiologic value. In Gabon, a warm, humid country in equatorial Africa, schoolchildren harbor an average of three different parasites capable of inducing hypereosinophilia or serum IgE elevation. These children's eosinophil counts start to rise at very young age, after weaning and contact with soil, and continue to increase rapidly until adulthood. Average values across all age groups are 1580 eosinophils/mm3 and 3300 kU IgE/L. Direct diagnosis of chronic parasitic infections is often possible in this setting, and specific treatments can be prescribed. In contrast, hypereosinophilia has less etiologic significance in patients originating from or having travelled to the tropics and who present to European parasitology units. Direct examination is rarely positive, and the etiologic diagnosis will thus be guided by epidemiologic, clinical and serologic findings. These findings are sometimes sufficient to initiate probabilistic treatment with albendazole, ivermectin and praziquentel.
Search on Google
Banco de datos:
MEDLINE
Asunto principal:
Eosinofilia
Tipo de estudio:
Diagnostic_studies
/
Screening_studies
Límite:
Animals
/
Humans
País como asunto:
Europa
Idioma:
Fr
Año:
2010
Tipo del documento:
Article