Hypoglycaemia-induced myocardial infarction as a result of sulphonylurea misuse.
Diabet Med
; 28(7): 876-9, 2011 Jul.
Article
en En
| MEDLINE
| ID: mdl-21204965
ABSTRACT
BACKGROUND:
Recent large-scale randomized trials of intensive therapy in Type 2 diabetes have reported increased cardiovascular morbidity and mortality in patient populations who experience a high frequency of hypoglycaemic events. However, there are few descriptions of hypoglycaemia leading directly to a myocardial infarction (MI) in the medical literature to date. CASE REPORT In this article we describe the case of a 76-year-old woman without diabetes who presented with symptoms, left bundle branch block and raised troponin, indicative of an MI. She was also noted to be hypoglycaemic with a plasma glucose level of 2.5 mmol/l. It was subsequently discovered that she had mistakenly been dispensed glibenclamide, a long-acting sulphonylurea, in the preceding weeks. Her cardiac symptoms resolved completely upon treatment of her hypoglycaemia and she had no significant coronary artery disease on angiography.CONCLUSION:
This is the first case of sulphonylurea-induced MI in a patient without diabetes and illustrates the adverse effects of acute hypoglycaemia upon the cardiovascular system.
Texto completo:
1
Banco de datos:
MEDLINE
Asunto principal:
Compuestos de Sulfonilurea
/
Diabetes Mellitus Tipo 2
/
Angiopatías Diabéticas
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Hipoglucemia
/
Infarto del Miocardio
Tipo de estudio:
Clinical_trials
/
Etiology_studies
Límite:
Aged
/
Female
/
Humans
Idioma:
En
Año:
2011
Tipo del documento:
Article