Evidence of central and peripheral vestibular pathology in blast-related traumatic brain injury.
Otol Neurotol
; 32(4): 571-80, 2011 Jun.
Article
en En
| MEDLINE
| ID: mdl-21358450
ABSTRACT
OBJECTIVE:
To prospectively assay the vestibular and oculomotor systems of blast-exposed service members with traumatic brain injury (TBI). STUDYDESIGN:
Prospective, nonblinded, nonrandomized descriptive study.SETTING:
Tertiary care facility (Department of Defense Medical Center). PATIENTS Twenty-four service members recovering from blast-related TBI sustained in Iraq or Afghanistan.INTERVENTIONS:
Focused history and physical, videonystagmography (VNG), rotational chair, cervical vestibular-evoked myogenic potentials, computerized dynamic posturography, and self-report measures.RESULTS:
Vestibular testing confirms a greater incidence of vestibular and oculomotor dysfunction in symptomatic (vestibular-like dizziness) personnel with blast-related TBI relative to asymptomatic group members. VNG in the symptomatic group revealed abnormal nystagmus or oculomotor findings in 6 of 12 subjects tested. Similarly, rotational chair testing in this group revealed evidence of both peripheral (4/12) and central (2/12) vestibular pathology. By contrast, the asymptomatic group revealed less vestibular impairment with 1 of 10 rotational chair abnormalities. The asymptomatic group was further characterized by fewer aberrant nystagmus findings (4/12 abnormal VNGs). Computerized dynamic posturography testing revealed no significant differences between groups. Self-report measures demonstrated differences between groups.CONCLUSION:
Vestibular function testing confirms a greater incidence of peripheral vestibular hypofunction in dizzy service members with blast-related TBI relative to those who are asymptomatic. Additionally, oculomotor abnormalities and/or nystagmus consistent with central involvement were present in 10 of the 24 study participants tested. The precise cause of these findings remains unknown.
Texto completo:
1
Banco de datos:
MEDLINE
Asunto principal:
Nervio Vestibular
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Traumatismos por Explosión
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Reflejo Vestibuloocular
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Lesiones Encefálicas
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Traumatismos del Nervio Oculomotor
Tipo de estudio:
Observational_studies
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Risk_factors_studies
Límite:
Adult
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Female
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Humans
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Male
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Middle aged
Idioma:
En
Año:
2011
Tipo del documento:
Article