Rational approach to treatment options for Lennox-Gastaut syndrome.
Epilepsia
; 52 Suppl 5: 10-20, 2011 Aug.
Article
en En
| MEDLINE
| ID: mdl-21790561
ABSTRACT
Lennox-Gastaut syndrome (LGS) is an intractable childhood-onset epileptic encephalopathy. Seizure freedom is rare in LGS. One of the hallmarks of LGS is medical intractability, with generally poor response to antiepileptic drugs (AEDs). Nevertheless, several treatment options are available that can mitigate the severity of seizures and curtail their frequency. New AEDs have been validated in randomized, controlled trials for the treatment of seizures in LGS. In some cases, nonpharmacologic options may be effective, although more data are needed to confirm efficacy outcomes. Comprehensive patient assessments are critical to achieve an optimal AED treatment regimen and minimize the potential for adverse effects.
Texto completo:
1
Ejes tematicos:
Pesquisa_clinica
Banco de datos:
MEDLINE
Asunto principal:
Espasmos Infantiles
/
Discapacidad Intelectual
/
Anticonvulsivantes
Tipo de estudio:
Clinical_trials
Límite:
Child
/
Child, preschool
/
Humans
Idioma:
En
Año:
2011
Tipo del documento:
Article