Fasciculations and their F-response revisited: high-density surface EMG in ALS and benign fasciculations.
Clin Neurophysiol
; 123(2): 399-405, 2012 Feb.
Article
en En
| MEDLINE
| ID: mdl-21820354
ABSTRACT
OBJECTIVE:
To compare the prevalence of fasciculation potentials (FPs) with F-responses between patients with amyotrophic lateral sclerosis (ALS) and patients with benign fasciculations.METHODS:
In seven patients with ALS and seven patients with benign fasciculations, high-density surface EMG was recorded for 15 min from the gastrocnemius muscle. Template matching was used to search for pairs of FPs with a repetition within 10-110 ms.RESULTS:
Interspike interval (ISI) histograms were constructed from 282 pairs of benign fasciculations and from 337 FP pairs in ALS. Peaks attributable to F-waves were found at latencies of 32 ms (benign) and 35 ms (ALS). Five patients with benign fasciculations and four patients with ALS had FPs with F-waves.CONCLUSIONS:
F-waves of FPs occur in both conditions - therefore they are not diagnostically helpful.SIGNIFICANCE:
F-waves confirm the distal origin of FPs for an individual axon. The occurrence of these FPs in a benign condition suggests that the generation of ectopic discharges in the distal axons is not specific to progressive neurodegeneration.
Texto completo:
1
Banco de datos:
MEDLINE
Asunto principal:
Potenciales de Acción
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Electromiografía
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Fasciculación
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Esclerosis Amiotrófica Lateral
Tipo de estudio:
Risk_factors_studies
Límite:
Adult
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Aged
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Female
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Humans
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Male
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Middle aged
Idioma:
En
Año:
2012
Tipo del documento:
Article