[A case of clinically mild encephalitis/encephalopathy with a reversible splenial lesion associated with anti-glutamate receptor antibody].
Rinsho Shinkeigaku
; 51(7): 510-3, 2011 Jul.
Article
en Ja
| MEDLINE
| ID: mdl-21823512
ABSTRACT
We report the case of an 18-year-old boy who presented with disturbance of consciousness and generalized seizures following flu-like symptoms such as high fever and arthralgia. T2 and diffusion weighted brain magnetic resonance images showed a hyperintense ovoid lesion in the splenium of the corpus callosum and T, weighted images showed a hypointense lesion; the lesion completely disappeared on repeat imaging after 3 days. Antiglutamate epsilon2 receptor antibodies were detected in his cerebrospinal fluid. Although the patient had several episodes of generalized seizures, he completely recovered within 3 months. Our patient had a clinically mild encephalitis/encephalopathy with a reversible splenial lesion following flu-like symptoms, which indicated viral infection. As compared to previously reported cases, our case was characteristic because of the protracted recovery shown by the patient. Anti-glutamate epsilon2 receptor antibodies may be associated with prolonged generalized seizures in the case of our patient. Our results also suggest that anti-glutamate epsilon2 receptor antibodies may play a role in the pathogenesis of this condition.
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Banco de datos:
MEDLINE
Asunto principal:
Autoanticuerpos
/
Receptores de Glutamato
/
Cuerpo Calloso
/
Encefalitis
Tipo de estudio:
Risk_factors_studies
Límite:
Adolescent
/
Humans
/
Male
Idioma:
Ja
Año:
2011
Tipo del documento:
Article